Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 7/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534991 | 0.82 | CHRM4 (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534635 | 0.81 | CHRM4 (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534666 | 0.81 | CHRM4 (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534846 | 0.79 | CHRM4 (0.44) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534821 | 0.79 | CHRM4 (0.38) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534672 | 0.76 | CHRM4 (0.39) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534833 | 0.76 | CHRM4 (0.41) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534819 | 0.75 | MAOB (0.43) | CHRM4CHRM2CHRM1MAOBMAOA | |
| SCHEMBL21535047 | 0.72 | MAOB (0.39) | CHRM4MAOBMAOA | |
| SCHEMBL21534621 | 0.72 | MAOB (0.39) | CHRM4MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |