Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | WNT1 | P04628 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21534822 | 0.87 | SPHK1 (0.41) | HRH3POLBLMNA | |
| SCHEMBL21534898 | 0.84 | KDM4E (0.40) | HRH3POLBLMNA | |
| SCHEMBL21534879 | 0.83 | PDK2 (0.40) | POLBLMNA | |
| SCHEMBL21534953 | 0.81 | CHRM4 (0.37) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL21534846 | 0.81 | CHRM4 (0.44) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL15537661 | 0.80 | PIK3CA (0.44) | CHRM2CHRM5CHRM1CHRM3PIK3CA | |
| SCHEMBL15537662 | 0.80 | PIK3CA (0.44) | CHRM2CHRM5CHRM1CHRM3PIK3CA | |
| SCHEMBL15539882 | 0.80 | PIK3CA (0.44) | CHRM2CHRM5CHRM1CHRM3PIK3CA | |
| SCHEMBL21534994 | 0.79 | MAOB (0.39) | HRH3POLBLMNA | |
| SCHEMBL21534991 | 0.78 | CHRM4 (0.40) | CHRM4CHRM2CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2858986-B1 | PIPERIDINE DERIVATIVES AS GPR119 AGONISTS | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-10-30 | — | — | EP | disclosed |