Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 5/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16803879 | 0.93 | PDK2 (0.43) | SPHK1SPHK2DPP4PDK2HTR1A | |
| SCHEMBL16803937 | 0.91 | DPP4 (0.43) | SPHK1SPHK2DPP4PDK2HTR1A | |
| SCHEMBL16803775 | 0.90 | PDK2 (0.41) | SPHK1SPHK2DPP4PDK2HTR1A | |
| SCHEMBL21534659 | 0.90 | PDK2 (0.41) | SPHK1SPHK2DPP4PDK2HTR1A | |
| SCHEMBL15537935 | 0.88 | PDK2 (0.39) | DPP4PDK2HTR1AHTR7PIK3CA | |
| SCHEMBL21535007 | 0.84 | HRH3 (0.42) | PDK2SSTR5 | |
| SCHEMBL20053698 | 0.83 | SSTR5 (0.34) | DPP4PIK3CASSTR5PIK3CDPIK3CB | |
| SCHEMBL21534966 | 0.83 | HRH3 (0.42) | PDK2SSTR5 | |
| SCHEMBL20053632 | 0.83 | PDK2 (0.43) | SPHK1SPHK2DPP4PDK2HTR1A | |
| SCHEMBL15540337 | 0.82 | SSTR5 (0.52) | SSTR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944600-B2 | Piperidine derivatives for GPR119 agonist | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2018-04-17 | — | — | US | disclosed |