Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21538195 | 0.98 | ALOX5 (0.35) | ALOX5APPAKT1PTPN1NR1H4 | |
| SCHEMBL22863233 | 0.94 | ALOX5 (0.35) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL23941689 | 0.94 | ALOX5 (0.35) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL13746651 | 0.94 | APP (0.35) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL9880204 | 0.93 | ALOX5 (0.45) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL9880202 | 0.93 | ALOX5 (0.45) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL9880205 | 0.90 | ALOX5 (0.44) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL23941207 | 0.90 | ALOX5 (0.37) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL24619629 | 0.90 | ALOX5 (0.37) | ALOX5APPPTPN1NR1H4BACE1 | |
| SCHEMBL9880206 | 0.90 | ALOX5 (0.44) | ALOX5APPPTPN1NR1H4BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49351-E1 | Cytoprotective agent | BIOGEN MA INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-RE47684-E1 | Cytoprotective agent | TMS CO., LTD. (JP) | 2019-11-05 | — | — | US | disclosed |