Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGB | P11216 | 8/20 | 0.36 |
| ▸ | PYGL | P06737 | 3/20 | 0.36 |
| ▸ | PYGM | P11217 | 2/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18537499 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL3412930 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL13559216 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL18681231 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL12658343 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL16918679 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL13010055 | 1.00 | PYGB (0.36) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL12899851 | 0.77 | PYGB (0.38) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL13787598 | 0.77 | PYGB (0.38) | PYGBPYGLPYGMOGALMNA | |
| SCHEMBL12929272 | 0.77 | PYGB (0.38) | PYGBPYGLPYGMOGALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10463683-B2 | Isotopologues of 5-azacytidine | CELGENE CORPORATION (US) | 2019-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10463683-B2 | Isotopologues of 5-azacytidine | UNG, DCTD, DPYD | PYGB 384/4885PYGL 27/4885PYGM 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.