Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TYMP | P19971 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21417605 | 0.90 | P2RX3 (0.41) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL17860563 | 0.86 | TYMP (0.40) | TYMPKDM4EP2RY1POLB | |
| SCHEMBL17860594 | 0.84 | P2RX3 (0.43) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21539862 | 0.82 | P2RX3 (0.45) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL17860537 | 0.82 | P2RX3 (0.45) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL21417368 | 0.81 | P2RX3 (0.46) | ALDH1A1LMNAALBMAPK1TYMP | |
| SCHEMBL5694043 | 0.81 | SLC29A1 (0.38) | LMNAP2RY1 | |
| SCHEMBL17860491 | 0.80 | P2RY12 (0.39) | TYMPP2RY1 | |
| SCHEMBL17860588 | 0.80 | ADORA1 (0.40) | P2RY1POLB | |
| SCHEMBL21540037 | 0.79 | P2RX3 (0.46) | ALDH1A1LMNAALBMAPK1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233882-B1 | FLUORINATED CYCLIC DINUCLEOTIDES FOR CYTOKINE INDUCTION | KAYLA THERAPEUTICS (FR) | 2019-10-30 | — | — | EP | disclosed |