Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 9/20 | 0.67 |
| ▸ | FKBP1A | P62942 | 10/20 | 0.60 |
| ▸ | FKBP1B | P68106 | 2/20 | 0.50 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17884418 | 0.85 | FKBP5 (0.52) | FKBP5FKBP1AL3MBTL1 | |
| SCHEMBL18107946 | 0.85 | FKBP5 (0.67) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL18107947 | 0.85 | FKBP5 (0.67) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL19946482 | 0.83 | FKBP5 (0.65) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16585988 | 0.83 | FKBP5 (0.74) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL18122820 | 0.83 | FKBP5 (0.74) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16585986 | 0.83 | FKBP5 (0.74) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL18107924 | 0.83 | FKBP5 (0.62) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL16586180 | 0.82 | FKBP5 (0.76) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 | |
| SCHEMBL21518629 | 0.82 | FKBP5 (0.76) | FKBP5FKBP1AFKBP1BFKBP4TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030556-B1 | SELECTIVE FKBP51 LIGANDS FOR TREATMENT OF PSYCHIATRIC DISORDERS | UNIV DARMSTADT TECH (DE) | 2019-10-30 | — | — | EP | disclosed |