SCHEMBL21541166

SCHEMBL21541166

CCC[C@H](CCCNC(=N)N)N(C)C

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
KMT2A Q03164 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALOX15 P16050 1/20 0.33
DPP7 Q9UHL4 1/20 0.31
GRIN2D O15399 1/20 0.30
GRIN3B O60391 1/20 0.30
GRIN1 Q05586 1/20 0.30
GRIN2A Q12879 1/20 0.30
GRIN2B Q13224 1/20 0.30
GRIN2C Q14957 1/20 0.30
GRIN3A Q8TCU5 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20099657 0.88 MEN1 (0.37) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL20104611 0.85 ALOX15 (0.34) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL21424858 0.81 MEN1 (0.35) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL23436542 0.75 MEN1 (0.31) MEN1CYP1A2KMT2ASMN1; SMN2
SCHEMBL22688615 0.75 DPP7 (0.40) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL20104600 0.75 MEN1 (0.35) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL20104599 0.74 NPY4R (0.33) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL21559886 0.74 MEN1 (0.33) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15
SCHEMBL20031685 0.74 NPY4R (0.40)
SCHEMBL24638158 0.74 DPP7 (0.42) MEN1CYP1A2KMT2ASMN1; SMN2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10875902-B2 Glucagon like peptide 1 (GLP-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof JANSSEN PHARMACEUTICA NV (BE) 2020-12-29 US disclosed
US-20190330296-A1 GLUCAGON LIKE PEPTIDE 1 (GLP-1) FUSION PEPTIDE COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE CONJUGATES AND USES THEREOF JANSSEN PHARMACEUTICA NV (BE) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10875902-B2 Glucagon like peptide 1 (GLP-1) fusion peptide coupled cyclic peptide tyrosine tyrosine conjugates and uses thereof GLP1R, GIPR, IAPP MEN1 1397/4885CYP1A2 4757/4885KMT2A 3695/4885
US-20190330296-A1 GLUCAGON LIKE PEPTIDE 1 (GLP-1) FUSION PEPTIDE COUPLED CYCLIC PEPTIDE TYROSINE TYROSINE CONJUGATES AND USES THEREOF GLP1R, GIPR, IAPP MEN1 1397/4885CYP1A2 4757/4885KMT2A 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.