Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21560737 | 1.00 | TOP2A (0.42) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL21560758 | 1.00 | TOP2A (0.42) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL21560823 | 1.00 | TOP2A (0.42) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL21560936 | 0.98 | PIK3CA (0.43) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL21560729 | 0.92 | NR1H2 (0.40) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL14030752 | 0.88 | NR1H2 (0.42) | CDK8NR1H2NR1H3TNFADORA1 | |
| SCHEMBL10032425 | 0.86 | IKBKB (0.52) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL3289250 | 0.84 | PIK3CA (0.53) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL28868 | 0.84 | IKBKB (0.53) | TOP2AIKBKBCHUKDAPK3JAK2 | |
| SCHEMBL28859500 | 0.84 | IKBKB (0.53) | TOP2AIKBKBCHUKDAPK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190348614-A1 | ELECTRON TRANSPORTING LAYERS, ORGANIC ELECTROLUMINESCENCE DEVICES, AND DISPLAYS | KUNSHAN GOVISIONOX OPTOELECTRONICS CO LTD (CN) | 2019-11-14 | — | — | US | disclosed |
| US-20190348614-A1 | ELECTRON TRANSPORTING LAYERS, ORGANIC ELECTROLUMINESCENCE DEVICES, AND DISPLAYS | KUNSHAN GOVISIONOX OPTOELECTRONICS CO LTD (CN) | 2019-11-14 | — | — | US | disclosed |