Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 5/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | USP7 | Q93009 | 2/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21560758 | 0.88 | TOP2A (0.42) | NR1H2NR1H3ADORA1ADORA2ACDK8 | |
| SCHEMBL21560737 | 0.88 | TOP2A (0.42) | NR1H2NR1H3ADORA1ADORA2ACDK8 | |
| SCHEMBL21542546 | 0.88 | TOP2A (0.42) | NR1H2NR1H3ADORA1ADORA2ACDK8 | |
| SCHEMBL21560823 | 0.88 | TOP2A (0.42) | NR1H2NR1H3ADORA1ADORA2ACDK8 | |
| SCHEMBL30596581 | 0.87 | CCR1 (0.50) | NPC1ADORA1ADORA2ANFKB1SMN1; SMN2 | |
| SCHEMBL21560936 | 0.87 | PIK3CA (0.43) | NR1H2NR1H3ADORA1ADORA2ACDK8 | |
| SCHEMBL31171152 | 0.85 | TOP1 (0.42) | NR1H2NR1H3NPC1RAB9AMEN1 | |
| SCHEMBL21560729 | 0.84 | NR1H2 (0.40) | NR1H2NR1H3ENPP1CDK8TNF | |
| SCHEMBL13872016 | 0.82 | L3MBTL1 (0.46) | NR1H2NR1H3ENPP1NPC1RAB9A | |
| SCHEMBL1125505 | 0.78 | NR1H2 (0.64) | NR1H2NR1H3ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080246395-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) | 2008-10-09 | — | — | US | disclosed |
| US-20080246395-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) | 2008-10-09 | — | — | US | disclosed |