SCHEMBL21545802

SCHEMBL21545802

O=C(O)Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1

nearest known ligand 0.59

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.59
DNMT1 P26358 5/20 0.54
ADRB1 P08588 1/20 0.54
ABL1 P00519 1/20 0.52
RIN1 Q13671 1/20 0.52
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
TK1 P04183 1/20 0.43
DNMT3B Q9UBC3 1/20 0.43
NT5E P21589 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3627002 0.91 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL22942033 0.91 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL21011276 0.91 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL20346239 0.91 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL3626999 0.91 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL3063781 0.90 DNMT1 (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL29983671 0.90 POLB (0.56) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL264065 0.88 POLB (0.76) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL28795634 0.88 POLB (0.76) POLBDNMT1ADRB1ABL1RIN1
SCHEMBL14733368 0.88 POLB (0.76) POLBDNMT1ADRB1ABL1RIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264164-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY TRILINK BIOTECHNOLOGIES, LLC 2023-08-24 US disclosed
US-11612873-B2 Homopolymer encoded nucleic acid memory Molecular Assemblies, Inc. (US) 2023-03-28 US disclosed
WO-2020219853-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. (US) 2020-10-29 WO disclosed
US-20190344239-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. 2019-11-14 US disclosed