SCHEMBL264065

SCHEMBL264065

O=C(Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.76
ABL1 P00519 1/20 0.68
RIN1 Q13671 1/20 0.68
P2RY6 Q15077 2/20 0.52
P2RY14 Q15391 2/20 0.52
NT5E P21589 2/20 0.52
DNMT1 P26358 5/20 0.49
ADRB1 P08588 1/20 0.49
DNMT3B Q9UBC3 1/20 0.42
DUT P33316 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14733368 1.00 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL28795634 1.00 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
SCHEMBL264066 1.00 POLB (0.76) POLBABL1RIN1P2RY6P2RY14
Phosphoric Acid SCHEMBL23748501 0.97 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL6524192 0.95 POLB (0.70) POLBABL1RIN1P2RY6P2RY14
SCHEMBL9706035 0.94 POLB (0.68) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14429249 0.93 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14568629 0.93 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14568644 0.93 POLB (0.72) POLBABL1RIN1P2RY6P2RY14
SCHEMBL14429239 0.93 POLB (0.72) POLBABL1RIN1P2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114652836-A T3SS small-molecule inhibitor and screening method and application thereof 山东大学 2022-06-24 CN claimed
CN-114369123-A Efficient preparation method of 5' -aminodeoxynucleoside 山东明化新材料有限公司 2022-04-19 CN claimed
EP-0548189-B1 A METHOD OF LINKING NUCLEOSIDES WITH A SILOXANE BRIDGE STERLING WINTHROP INC (US) 1994-12-28 EP claimed
EP-4741411-A2 OLIGONUCLEOTIDE PRODUCTION METHOD, AND NUCLEOSIDE, NUCLEOTIDE, OR OLIGONUCLEOTIDE AJINOMOTO CO., INC. (JP) 2026-05-13 EP disclosed
US-12559517-B2 Oligonucleotide manufacturing method AJINOMOTO CO., INC. (JP) 2026-02-24 US disclosed
EP-4606903-A1 METHOD FOR ENZYMATIC SYNTHESIS OF NUCLEOSIDE CONTAINING PROTECTING GROUP, AND COMPOSITION Asymchem Life Science (Tianjin) Co., Ltd (CN) 2025-08-27 EP disclosed
US-20250242036-A1 TRANS-MEMBRANE DELIVERY SYSTEMS AND USES THEREOF APOSENSE LTD. (IL) 2025-07-31 US disclosed
EP-4590338-A1 TRANS-MEMBRANE DELIVERY SYSTEMS AND USES THEREOF Aposense Ltd. (IL) 2025-07-30 EP disclosed
CN-113151261-B Antisense oligonucleotides as inhibitors of TGF-R signaling 神经视觉医药有限公司 2025-06-17 CN disclosed
EP-3681897-B1 N4-MODIFIED CYTIDINE NUCLEOTIDES AND THEIR USE UNIV VILNIUS (LT) 2025-05-14 EP disclosed
EP-4516901-A1 A METHOD FOR SCREENING OF HYDROLYTIC ENZYMES Vilnius University (LT) 2025-03-05 EP disclosed
EP-0168342-A1 Process for the preparation of thrombin inhibitors CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
EP-0146785-A1 Process for the preparation of protease inhibitors CIBA-GEIGY AG (CH) 1985-07-03 EP disclosed
EP-0061746-B1 PHOSPHORAMIDITE COMPOUNDS AND THEIR USE IN PRODUCING OLIGONUCLEOTIDES UNIVERSITY PATENTS, INC. (US) 1985-03-20 EP disclosed
US-4500707-A Nucleosides useful in the preparation of polynucleotides UNIVERSITY PATENTS, INC. (US) 1985-02-19 US disclosed
US-4457867-A VIRICIDES, ANTITUMOR ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-07-03 US disclosed
EP-0083777-A1 Physiologically active peptide with between 147 and 162 amino acid residues Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-20 EP disclosed
EP-0073826-A1 RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION BIORESEARCH INC. (US) 1983-03-16 EP disclosed
EP-0061746-A1 Phosphoramidite compounds and their use in producing oligonucleotides UNIVERSITY PATENTS, INC. (US) 1982-10-06 EP disclosed
WO-1982003079-A1 RAPID SOLID PHASE SYNTHESIS OF OLIGONUCLEOTIDES USING PHOSPHORUS OXYCHLORIDE ACTIVATION BIORESEARCH INC (US) 1982-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250242036-A1 TRANS-MEMBRANE DELIVERY SYSTEMS AND USES THEREOF HAVCR2, SLC47A2, SLC47A1 POLB 1430/4885ABL1 1904/4885RIN1 1615/4885
US-12559517-B2 Oligonucleotide manufacturing method POLL, IGF2BP1, POLI POLB 25/4885ABL1 1538/4885RIN1 1418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.