SCHEMBL21545820

SCHEMBL21545820

CC(C)(C)[Si](C)(C)OC[C@H]1O[C@@H](n2cnc3c(Cl)nc(N)nc32)C[C@@H]1O

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NT5E P21589 2/20 0.54
▸ PNP P00491 1/20 0.52
▸ LMNA P02545 1/20 0.52
▸ TP53 P04637 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ PDE4D Q08499 1/20 0.52
▸ PDE3A Q14432 1/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ RXFP1 Q9HBX9 1/20 0.52
▸ POLB P06746 2/20 0.47
▸ CYP1A2 P05177 1/20 0.46
▸ HBB P68871 1/20 0.46
▸ TYMP P19971 1/20 0.44
▸ ADRB1 P08588 1/20 0.44
▸ DNMT1 P26358 1/20 0.44
▸ ENPP1 P22413 1/20 0.43
▸ P2RY1 P47900 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887526 1.00 NT5E (0.54) NT5EPNPLMNATP53HTT
SCHEMBL10022904 1.00 NT5E (0.54) NT5EPNPLMNATP53HTT
SCHEMBL10427400 0.87 PNP (0.70) NT5EPNPLMNATP53HTT
SCHEMBL10427399 0.87 PNP (0.70) NT5EPNPLMNATP53HTT
SCHEMBL29479238 0.87 PNP (0.70) NT5EPNPLMNATP53HTT
SCHEMBL21545801 0.85 HIF1A (0.53) NT5EPNPLMNATP53HTT
SCHEMBL21563842 0.85 HIF1A (0.53) NT5EPNPLMNATP53HTT
SCHEMBL21563934 0.85 HIF1A (0.53) NT5EPNPLMNATP53HTT
SCHEMBL9684332 0.83 NT5E (0.44) NT5EPNPLMNATP53HTT
SCHEMBL24370786 0.83 POLB (0.65) NT5EPNPLMNATP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230264164-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY TRILINK BIOTECHNOLOGIES, LLC 2023-08-24 — — US disclosed
US-11612873-B2 Homopolymer encoded nucleic acid memory Molecular Assemblies, Inc. (US) 2023-03-28 — — US disclosed
WO-2020219853-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. (US) 2020-10-29 — — WO disclosed
US-20190344239-A1 HOMOPOLYMER ENCODED NUCLEIC ACID MEMORY Molecular Assemblies, Inc. 2019-11-14 — — US disclosed
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