Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 3/20 | 0.44 |
| ▸ | AHCY | P23526 | 2/20 | 0.43 |
| ▸ | HINT1 | P49773 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705853 | 0.84 | AHCY (0.46) | NT5EAHCYHINT1PDE4DPDE3A | |
| SCHEMBL887526 | 0.83 | NT5E (0.54) | NT5ELMNATP53PNPHTT | |
| SCHEMBL10022904 | 0.83 | NT5E (0.54) | NT5ELMNATP53PNPHTT | |
| SCHEMBL21545820 | 0.83 | NT5E (0.54) | NT5ELMNATP53PNPHTT | |
| SCHEMBL9471667 | 0.83 | NT5E (0.35) | NT5EAHCYHINT1HSP90B1HSP90AA1 | |
| SCHEMBL9470316 | 0.81 | AHCY (0.54) | NT5EAHCYLMNATP53PNP | |
| SCHEMBL4897987 | 0.78 | ABCB1 (0.39) | NT5EAHCYHINT1PDE4DABCB1 | |
| SCHEMBL15900209 | 0.77 | ADORA2A (0.54) | NT5EADORA3 | |
| SCHEMBL15198000 | 0.77 | NT5E (0.38) | NT5EAHCYHINT1LMNATP53 | |
| SCHEMBL20691349 | 0.77 | AHCY (0.41) | NT5EAHCYHINT1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153352-A | Viricides and antitumor agent | BRISTOL-MYERS SQUIBB COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0366059-A2 | Carbocyclic nucleoside analogs | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-05-02 | — | — | EP | disclosed |