SCHEMBL21546916

SCHEMBL21546916

Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C(F)(F)F)cc(-n3c4ccccc4c4cc(-c5ccc(C)cc5C)ccc43)c2-c2cccc(C#N)c2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAT2A P31153 1/20 0.36
HCRTR1 O43613 2/20 0.35
HCRTR2 O43614 2/20 0.35
PDK2 Q15119 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.35
PTPN5 P54829 1/20 0.34
ENPP1 P22413 2/20 0.34
CETP P11597 1/20 0.34
AR P10275 2/20 0.33
ELANE P08246 3/20 0.33
PTGER4 P35408 1/20 0.32
TRPA1 O75762 1/20 0.32
GRM5 P41594 1/20 0.32
PRF1 P14222 1/20 0.32
CNR2 P34972 2/20 0.31
CNR1 P21554 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21546718 0.96 MAT2A (0.38) MAT2AHCRTR1HCRTR2PDK2PTGDR2
SCHEMBL21547104 0.95 MAT2A (0.36) MAT2AHCRTR1HCRTR2PDK2PTGDR2
SCHEMBL20617170 0.92 AR (0.34) MAT2AARPTGER4
SCHEMBL21546931 0.92 AR (0.42) MAT2APDK2PTGDR2PTPN5ENPP1
SCHEMBL21546711 0.92 MAT2A (0.38) MAT2AHCRTR1HCRTR2PDK2PTGDR2
SCHEMBL21546844 0.91 MAT2A (0.40) MAT2APDK2PTGDR2PTPN5ENPP1
SCHEMBL21546947 0.91 ELANE (0.36) PDK2ARELANEPTGER4PRF1
SCHEMBL22760735 0.91 MAT2A (0.41) MAT2AHCRTR1HCRTR2PDK2PTGDR2
SCHEMBL19903428 0.90 AR (0.34) ARPTGER4
SCHEMBL21547039 0.90 AR (0.41) MAT2APDK2PTGDR2PTPN5ENPP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10981930-B2 Organic molecules for use in optoelectronic devices CYNORA GMBH (DE) 2021-04-20 US disclosed
US-20200385399-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2020-12-10 US disclosed
EP-3478793-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-11-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10981930-B2 Organic molecules for use in optoelectronic devices OR10J3, OR51E2, EPCAM MAT2A 1149/4885HCRTR1 846/4885HCRTR2 288/4885
US-20200385399-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES OR10J3, OR51E2, EPCAM MAT2A 1149/4885HCRTR1 846/4885HCRTR2 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.