Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20307137 | 0.91 | EPHX1 (0.56) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL18265739 | 0.83 | EPHX1 (0.63) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL17035439 | 0.83 | EPHX1 (0.38) | EPHX1SMN1; SMN2 | |
| SCHEMBL17050226 | 0.81 | KCNA3 (0.37) | EPHX1SMN1; SMN2CCNE1CDK2GSK3B | |
| SCHEMBL28077322 | 0.80 | NAAA (0.39) | EPHX1HTTSMN1; SMN2 | |
| SCHEMBL27870934 | 0.78 | EPHX1 (0.36) | EPHX1HTT | |
| SCHEMBL965658 | 0.78 | EPHX1 (0.96) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL15777906 | 0.78 | EPHX1 (0.89) | EPHX1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL28019641 | 0.77 | BCHE (0.48) | EPHX1ALDH1A1BCHE | |
| SCHEMBL20798246 | 0.77 | CYP3A4 (0.35) | MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110418-B1 | ARYL, HETEROARYL, AND HETEROCYCLIC COMPOUNDS FOR TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ACHILLION PHARMACEUTICALS INC (US) | 2019-11-06 | — | — | EP | disclosed |