⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8930516 | 0.83 | — | — | |
| SCHEMBL1004709 | 0.76 | — | — | |
| SCHEMBL156013 | 0.74 | — | — | |
| SCHEMBL3951490 | 0.64 | — | — | |
| SCHEMBL1383854 | 0.63 | — | — | |
| SCHEMBL994101 | 0.63 | — | — | |
| SCHEMBL31694674 | 0.61 | — | — | |
| SCHEMBL28099752 | 0.61 | — | — | |
| SCHEMBL3501288 | 0.61 | ALDH1A1 (0.33) | — | |
| SCHEMBL156015 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011081939-A1 | DIRECT SENSING OF MOLECULAR SPECIES BY POLYFLUORS ON A DNA BACKBONE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
| WO-2003042658-A2 | METHODS AND COMPOSITIONS FOR ENHANCING DETECTION IN DETERMINATIONS EMPLOYING CLEAVABLE ELECTROPHORETIC TAG REAGENTS | ACLARA BIOSCIENCES, INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| EP-0549615-A4 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS INC (US) | 1997-08-27 | — | — | EP | disclosed |
| WO-1995031434-A1 | COMPLEMENTARY DNA AND TOXINS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1995-11-23 | — | — | WO | disclosed |
| EP-0549615-A1 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992003568-A1 | SUGAR MODIFIED OLIGONUCLEOTIDES THAT DETECT AND MODULATE GENE EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 1992-03-05 | — | — | WO | disclosed |