Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.69 |
| ▸ | HTR3A | P46098 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467563 | 0.82 | HRH4 (1.00) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL31749043 | 0.81 | HRH4 (0.74) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL5237102 | 0.80 | HTR3A (0.72) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL31214382 | 0.79 | HTR3A (0.70) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL31214324 | 0.79 | HRH4 (0.70) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL13801322 | 0.78 | HRH4 (0.72) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL23771247 | 0.74 | HDAC11 (0.63) | HTR3ARAB9APDE10ABCHEACHE | |
| SCHEMBL605362 | 0.74 | HRH4 (0.62) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL27563614 | 0.72 | HRH4 (0.62) | HRH4HTR3AKDM4EALDH1A1GAA | |
| SCHEMBL5237605 | 0.69 | HRH4 (0.62) | HRH4HTR3APDE10ABCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564240-A1 | PIPERIDINE INTERMEDIATES | Purdue Pharma L.P. (US) | 2019-11-06 | — | — | EP | disclosed |