Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.47 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17363942 | 0.98 | CHRNB4 (0.54) | CHRNB4CHRNA3CHRNA7SIGMAR1KCNH2 | |
| Water SCHEMBL28125747 | 0.96 | CHRNB4 (0.53) | CHRNB4CHRNA3CHRNA7SIGMAR1KCNH2 | |
| Bromide SCHEMBL11132581 | 0.90 | KCNH2 (0.53) | CHRNB4CHRNA3CHRNA7SIGMAR1KCNH2 | |
| SCHEMBL5544154 | 0.90 | CYP1A2 (0.54) | CHRNB4CHRNA3CHRNA7SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL11881433 | 0.88 | KCNH2 (0.60) | CHRNB4CHRNA3CHRNA7SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL5092755 | 0.87 | CHRNA7 (0.56) | CHRNB4CHRNA3CHRNA7KCNH2CHRM2 | |
| Iodide SCHEMBL9670776 | 0.85 | KCNH2 (0.55) | CHRNB4CHRNA3CHRNA7KCNH2CHRM2 | |
| SCHEMBL12540912 | 0.85 | CHRNA7 (0.58) | CHRNB4CHRNA3CHRNA7KCNH2CHRM2 | |
| Bromide SCHEMBL11131159 | 0.83 | KCNH2 (0.64) | SIGMAR1KCNH2MEN1KMT2A | |
| Bromide SCHEMBL11137779 | 0.83 | KCNH2 (0.64) | SIGMAR1KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106565536-A | Isolongifolenone oxime ether derivative, and preparation method and application thereof | 广西民族大学 | 2017-04-19 | — | — | CN | claimed |
| US-20240002612-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | TORAY INDUSTRIES, INC. (JP) | 2024-01-04 | — | — | US | disclosed |
| EP-4257624-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | Toray Industries, Inc. (JP) | 2023-10-11 | — | — | EP | disclosed |
| CN-116507653-A | Drawn fiber-reinforced molded article | 东丽株式会社 | 2023-07-28 | — | — | CN | disclosed |
| WO-2022118827-A1 | FIBER-REINFORCED PULTRUSION-MOLDED ARTICLE | 東レ株式会社 | 2022-06-09 | — | — | WO | disclosed |
| CN-107430343-B | Composition for forming cationically polymerizable resist underlayer film | 日产化学工业株式会社 | 2020-10-30 | — | — | CN | disclosed |
| US-10437151-B2 | Cationically polymerizable resist underlayer film-forming composition | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-10-08 | — | — | US | disclosed |
| US-20180081274-A1 | CATIONICALLY POLYMERIZABLE RESIST UNDERLAYER FILM-FORMING COMPOSITION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-03-22 | — | — | US | disclosed |
| CN-106565536-A | Isolongifolenone oxime ether derivative, and preparation method and application thereof | 广西民族大学 | 2017-04-19 | — | — | CN | disclosed |
| WO-2011081937-A1 | CORTICOSTEROID-BETA-AGONIST-MUSCARINIC ANTAGONIST COMPOUNDS FOR USE IN THERAPY | GILEAD SCIENCES, INC. (US) | 2011-07-07 | — | — | WO | disclosed |
| US-20090306375-A1 | Process for production of 4(3H)-quinazolinone derivative | MSD K.K. (JP) | 2009-12-10 | — | — | US | disclosed |
| EP-1900733-A1 | PROCESS FOR PRODUCTION OF 4(3H)-QUINAZOLINONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |
| EP-0264880-B1 | FLUORINE DERIVATIVES OF VITAMIN D3 AND PROCESS FOR PRODUCING THE SAME | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4931474-A | Ether derivative and an acaricidal or insecticidal composition comprising said derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-06-05 | — | — | US | disclosed |
| US-4853378-A | Fluorine derivatives of vitamin D3 and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0264880-A1 | Fluorine derivatives of vitamin D3 and process for producing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-04-27 | — | — | EP | disclosed |
| EP-0255935-A1 | An ether derivative and an acaricidal or insecticidal composition comprising said derivative | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-02-17 | — | — | EP | disclosed |