SCHEMBL21549385

SCHEMBL21549385

CC[C@@H](Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1)Nc1ccc(C(=O)NCCC(=O)O)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GCGR P47871 15/20 0.53
ADCY6 O43306 3/20 0.53
ADCY3 O60266 3/20 0.53
ADCY9 O60503 3/20 0.53
ADCY5 O95622 3/20 0.53
ADCY8 P40145 3/20 0.53
ADCY7 P51828 3/20 0.53
ADCY2 Q08462 3/20 0.53
ADCY1 Q08828 3/20 0.53
ADCY4 Q8NFM4 3/20 0.53
EPHX2 P34913 3/20 0.51
PPARG P37231 2/20 0.51
PPARA Q07869 1/20 0.51
GIPR P48546 2/20 0.50
GCG P01275 2/20 0.47
GLP1R P43220 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21528692 0.90 GCGR (0.50) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528895 0.90 GCGR (0.50) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528694 0.90 GCGR (0.50) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528963 0.90 GCGR (0.53) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528965 0.90 GCGR (0.53) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL20425602 0.88 GCGR (0.48) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528700 0.88 GCGR (0.48) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528651 0.88 GCGR (0.55) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528647 0.88 GCGR (0.55) GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL21528503 0.87 GCGR (0.49) GCGRADCY6ADCY3ADCY9ADCY5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11384060-B2 Amide compounds and use thereof ALPHALA CO., LTD. (TW) 2022-07-12 US disclosed
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF ALPHALA CO., LTD. (TW) 2019-11-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190337915-A1 AMIDE COMPOUNDS AND USE THEREOF GLP1R, IAPP, GPR119 GCGR 4/4885ADCY6 68/4885ADCY3 25/4885
US-11384060-B2 Amide compounds and use thereof GLP1R, IAPP, GPR119 GCGR 4/4885ADCY6 68/4885ADCY3 25/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.