Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 20/20 | 1.00 |
| ▸ | TRPC3 | Q13507 | 17/20 | 1.00 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23068128 | 1.00 | TRPC6 (1.00) | TRPC6TRPC3TRPC7 | |
| SCHEMBL23068172 | 0.91 | TRPC6 (1.00) | TRPC6TRPC3TRPC7 | |
| SCHEMBL21550534 | 0.91 | TRPC6 (1.00) | TRPC6TRPC3TRPC7 | |
| SCHEMBL23068129 | 0.85 | TRPC6 (0.73) | TRPC6TRPC3TRPC7 | |
| SCHEMBL21550289 | 0.84 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL21550286 | 0.84 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL23068144 | 0.84 | TRPC3 (1.00) | TRPC6TRPC3 | |
| SCHEMBL30355214 | 0.83 | TRPC6 (0.74) | TRPC6TRPC3TRPC7 | |
| SCHEMBL29025006 | 0.80 | TRPC6 (0.66) | TRPC6TRPC3TRPC7 | |
| SCHEMBL23068148 | 0.77 | TRPC6 (0.74) | TRPC6TRPC3TRPC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790870-A1 | CYCLOPENTANE COMPOUNDS | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) | 2021-03-17 | — | — | EP | claimed |
| WO-2019215268-A1 | CYCLOPENTANE COMPOUNDS | ASTRAZENECA AB (SE) | 2019-11-14 | — | — | WO | claimed |
| EP-3790870-A1 | CYCLOPENTANE COMPOUNDS | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD (CN) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215268-A1 | CYCLOPENTANE COMPOUNDS | ASTRAZENECA AB (SE) | 2019-11-14 | — | — | WO | disclosed |