SCHEMBL21551034

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21565578	0.82	HRH3 (0.60)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL13783890	0.81	HRH3 (0.82)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL578548	0.79	HRH3 (0.71)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL6813604	0.77	HRH3 (0.69)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL3669623	0.77	HRH3 (0.64)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL21550787	0.77	HRH3 (0.55)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL29725202	0.77	HRH3 (0.55)	HRH3USP2TSHRMEN1KMT2A
	SCHEMBL15467001	0.77	HRH3 (0.87)	HRH3MEN1KMT2ASMN1; SMN2MAPT
	SCHEMBL15367163	0.76	HTT (0.48)	HRH3TSHRNPC1SMN1; SMN2MAPK1
	SCHEMBL6555500	0.76	NPC1 (0.47)	HRH3TSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.