Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.51 |
| ▸ | NOS3 | P29474 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | NOS2 | P35228 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578548 | 0.98 | HRH3 (0.71) | HRH3NPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13783890 | 0.93 | HRH3 (0.82) | HRH3NPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL1926443 | 0.91 | HRH3 (0.65) | HRH3NPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15467001 | 0.88 | HRH3 (0.87) | HRH3ALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL1244075 | 0.83 | ALDH1A1 (0.73) | HRH3NPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL17873765 | 0.82 | HRH3 (0.71) | HRH3NPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL12665893 | 0.82 | HRH3 (0.53) | HRH3NPC1ALDH1A1KDM4EL3MBTL1 | |
| 4-(4-Chlorobenzyl)Morpholine SCHEMBL4103722 | 0.80 | HRH3 (0.74) | HRH3NPC1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6813696 | 0.80 | HRH3 (0.75) | HRH3ALDH1A1KDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL13362301 | 0.80 | HRH3 (0.74) | HRH3ALDH1A1SMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224364-A1 | Organo-zinc compounds | RIEKE METALS, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224364-A1 | Organo-zinc compounds | ZFX, CXXC5, CXXC4 | HRH3 2675/4885NPC1 629/4885ALDH1A1 2237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.