SCHEMBL21551907

SCHEMBL21551907

CCC(c1ccccc1)N1Cc2cc3c(cc2C[C@H]1C(=O)NC(Cc1ccc(-c2ccnc(C)c2C)cc1)C(=O)O)OC[C@H](c1ccc(OCc2ccc(Cl)c(Cl)c2)cc1)O3

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 19/20 1.00
AMY1A P0DUB6 1/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2019167 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL31709974 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL30069234 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL2019171 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL539631 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL30746800 1.00 GLP1R (1.00) GLP1RAMY1A
SCHEMBL539630 1.00 GLP1R (1.00) GLP1RAMY1A
Hydrochloric Acid SCHEMBL21552133 0.99 GLP1R (1.00) GLP1RAMY1A
Hydrochloric Acid SCHEMBL21552139 0.99 GLP1R (1.00) GLP1RAMY1A
Hydrochloric Acid SCHEMBL21552137 0.99 GLP1R (1.00) GLP1RAMY1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790549-A1 THERAPEUTIC USES OF GLP1R AGONISTS vTv Therapeutics LLC (US) 2021-03-17 EP claimed
WO-2019217165-A1 THERAPEUTIC USES OF GLP1R AGONISTS VTV THERAPEUTICS LLC (US) 2019-11-14 WO claimed
EP-3790549-A1 THERAPEUTIC USES OF GLP1R AGONISTS vTv Therapeutics LLC (US) 2021-03-17 EP disclosed
WO-2019217165-A1 THERAPEUTIC USES OF GLP1R AGONISTS VTV THERAPEUTICS LLC (US) 2019-11-14 WO disclosed