Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13844630 | 1.00 | TAAR1 (0.32) | TAAR1HTR3ATSHRNFKB1HIF1A | |
| SCHEMBL13717137 | 0.82 | — | — | |
| SCHEMBL17733803 | 0.81 | — | — | |
| SCHEMBL31195460 | 0.80 | LMNA (0.33) | — | |
| SCHEMBL14632167 | 0.80 | — | — | |
| SCHEMBL10777302 | 0.76 | — | — | |
| SCHEMBL17214551 | 0.76 | TAAR1 (0.33) | TAAR1 | |
| SCHEMBL11983413 | 0.76 | KDM4E (0.38) | TAAR1TSHRNFKB1HIF1AKDM4E | |
| SCHEMBL13980353 | 0.76 | — | — | |
| SCHEMBL13696257 | 0.74 | MAPT (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3048106-B1 | THIENOPYRIMIDINE AS INHIBITORS OF ATYPICAL PROTEIN KINASE C | CANCER RESEARCH TECH LTD (GB) | 2019-11-06 | — | — | EP | disclosed |