Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 5/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.80 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13126906 | 0.82 | CYP2C9 (0.63) | CYP2C19CYP2C9GAAALDH1A1KMT2A | |
| SCHEMBL18124767 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP2C9GAAALDH1A1MAOB | |
| SCHEMBL8998580 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP2C9GAAALDH1A1KDM4E | |
| SCHEMBL14619614 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP2C9GAAALDH1A1KDM4E | |
| SCHEMBL14619613 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP2C9GAAALDH1A1KDM4E | |
| SCHEMBL15482008 | 0.80 | CYP2C19 (0.56) | CYP2C19CYP2C9GAAALDH1A1KDM4E | |
| SCHEMBL13126888 | 0.78 | CYP2C9 (0.58) | CYP2C19CYP2C9ALDH1A1TSHRMAOB | |
| SCHEMBL7450000 | 0.78 | CYP2C19 (0.53) | CYP2C19CYP2C9GAAALDH1A1KDM4E | |
| SCHEMBL6779019 | 0.78 | CYP2C19 (0.53) | CYP2C19CYP2C9GAAALDH1A1TSHR | |
| SCHEMBL11309348 | 0.78 | CYP2C19 (0.53) | CYP2C19CYP2C9GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2022-04-19 | — | — | US | disclosed |
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | UNIV NANYANG TECH (SG) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337955-A1 | ACTIVATION OF CARBONYL BETA-CARBONS FOR CHEMICAL TRANSFORMATIONS | CBR1, CBR3, CAT | CYP2C19 127/4885CYP2C9 63/4885GAA 685/4885 |
| US-11306097-B2 | Activation of carbonyl beta-carbons for chemical transformations | CBR1, CBR3, CAT | CYP2C19 127/4885CYP2C9 63/4885GAA 685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.