Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5485798 | 0.99 | NLRP3 (0.35) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8206373 | 0.90 | NLRP3 (0.35) | NLRP3MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8579826 | 0.86 | MEN1 (0.33) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL8578003 | 0.85 | MEN1 (0.32) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL782117 | 0.85 | MEN1 (0.37) | NLRP3MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL769209 | 0.85 | MEN1 (0.37) | NLRP3MEN1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL8575814 | 0.85 | MEN1 (0.33) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL12461036 | 0.83 | TSHR (0.31) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL6306862 | 0.83 | MEN1 (0.37) | MEN1KMT2AL3MBTL1OPRM1 | |
| SCHEMBL8575773 | 0.82 | MEN1 (0.34) | NLRP3MEN1KMT2AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564225-A1 | CRYSTALLINE FORM OF SPIROMESIFEN | Bayer Aktiengesellschaft (DE) | 2019-11-06 | — | — | EP | disclosed |