⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17149224 | 0.75 | — | — | |
| SCHEMBL23408854 | 0.68 | GAA (0.40) | — | |
| SCHEMBL24293007 | 0.67 | — | — | |
| SCHEMBL18840324 | 0.62 | MAPK1 (0.30) | — | |
| SCHEMBL20158799 | 0.58 | — | — | |
| SCHEMBL12892575 | 0.58 | LMNA (0.33) | — | |
| SCHEMBL20158766 | 0.58 | — | — | |
| SCHEMBL19218112 | 0.56 | CHRM2 (0.32) | — | |
| SCHEMBL1906759 | 0.56 | — | — | |
| SCHEMBL18270925 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10711008-B2 | Indoline analogs and uses thereof | Oncternal Therapeutics, Inc. (US) | 2020-07-14 | — | — | US | disclosed |
| US-20190337951-A1 | INDOLINE ANALOGS AND USES THEREOF | GEORGETOWN UNIVERSITY | 2019-11-07 | — | — | US | disclosed |