Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 9/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GLB1 | P16278 | 2/20 | 0.46 |
| ▸ | MAN1B1 | Q9UKM7 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16991786 | 1.00 | GBA1 (0.46) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL21553504 | 0.80 | — | — | |
| SCHEMBL13979527 | 0.77 | APLNR (0.32) | MAN1B1 | |
| SCHEMBL15521047 | 0.72 | OGA (0.51) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL15521093 | 0.72 | OGA (0.51) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL2434063 | 0.72 | OGA (0.51) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL2272527 | 0.72 | OGA (0.51) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL18648594 | 0.71 | GBA1 (0.48) | GBA1FUCA1GLAGAAGLB1 | |
| SCHEMBL3319435 | 0.69 | — | — | |
| SCHEMBL29034779 | 0.68 | MAN1B1 (0.40) | GBA1FUCA1GLAGAAGLB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3105235-B1 | SUGAR DERIVATIVES COMPRISING SULFUR-CONTAINING MOIETIES AND METHODS OF MAKING SAME AND METHODS OF USING THE SAME FOR THE TREATMENT OF MPS IIIC | AMICUS THERAPEUTICS INC (US) | 2019-11-06 | — | — | EP | disclosed |