SCHEMBL21553579

SCHEMBL21553579

C=C/C(=C\C)CC(=O)NCC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CACNA1H O95180 1/20 0.33
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
THRA P10827 1/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12314775 0.73 ALDH1A1 (0.45) CACNA1HALDH1A1TSHRMAPK1TDP1
SCHEMBL138083 0.73 ALDH1A1 (0.54) ALDH1A1TSHRMAPK1TDP1THRA
SCHEMBL21553585 0.73 MCL1 (0.34) ALDH1A1TSHRMAPK1TDP1
SCHEMBL14902252 0.70 CACNA1H (0.35) CACNA1HALDH1A1TDP1
SCHEMBL8437331 0.70 CACNA1H (0.35) CACNA1H
Dimethylamine SCHEMBL9134759 0.69 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TDP1THRA
SCHEMBL23904591 0.68
SCHEMBL8964 0.68 MEN1 (0.50) CACNA1HALDH1A1TDP1
SCHEMBL14932882 0.68 CACNA1H (0.36) CACNA1H
SCHEMBL12028700 0.68 HPGD (0.46) CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2207522-B1 PERSONAL CARE AND HOUSEHOLD PRODUCT COMPOSITIONS COMPRISING SPECIFIC SULFUR CONTAINING STABILISER COMPOUNDS BASF SE (DE) 2019-11-06 EP disclosed