Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 19/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550895 | 0.89 | FURIN (0.56) | FURIN | |
| SCHEMBL29928557 | 0.89 | FURIN (0.56) | FURIN | |
| SCHEMBL29198900 | 0.82 | FURIN (0.53) | FURIN | |
| SCHEMBL21550909 | 0.80 | FURIN (0.56) | FURIN | |
| SCHEMBL21564564 | 0.79 | FURIN (0.53) | FURIN | |
| SCHEMBL29890782 | 0.79 | FURIN (0.53) | FURIN | |
| SCHEMBL21551389 | 0.73 | FURIN (0.59) | FURIN | |
| SCHEMBL21564397 | 0.72 | BRD4 (0.38) | FURIN | |
| SCHEMBL21550523 | 0.71 | FURIN (0.69) | FURIN | |
| SCHEMBL21551183 | 0.71 | FURIN (0.40) | FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-A1 | FURIN INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2021-03-17 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |