Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 15/20 | 0.53 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928557 | 0.92 | FURIN (0.56) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21550895 | 0.92 | FURIN (0.56) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21550909 | 0.89 | FURIN (0.56) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21564564 | 0.88 | FURIN (0.53) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL29890782 | 0.88 | FURIN (0.53) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21551389 | 0.82 | FURIN (0.59) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21553796 | 0.82 | FURIN (0.44) | FURIN | |
| SCHEMBL21550726 | 0.80 | FURIN (0.53) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL21551082 | 0.78 | FURIN (0.52) | FURINCACNA1IKCNH2FAAHBCHE | |
| SCHEMBL29928363 | 0.78 | FURIN (0.52) | FURINCACNA1IKCNH2FAAHBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112384509-B | Furin inhibitors | 葛兰素史密斯克莱知识产权发展有限公司 | 2024-04-30 | — | — | CN | disclosed |