Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.56 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.55 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.55 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.55 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.55 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.55 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21012396 | 1.00 | REN (0.56) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21554936 | 0.90 | REN (0.53) | REN | |
| SCHEMBL4394844 | 0.89 | CAPN1 (0.59) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3836761 | 0.89 | KLK5 (0.53) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL289669 | 0.89 | KLK5 (0.53) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16462573 | 0.89 | KLK5 (0.53) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21012316 | 0.87 | REN (0.60) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3841326 | 0.87 | CAPN1 (0.52) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21458009 | 0.87 | CAPN1 (0.52) | RENPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23921535 | 0.87 | KMT2A (0.53) | RENPSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3788031-B1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED S L (ES) | 2023-09-27 | — | — | EP | disclosed |
| EP-3788031-B1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED S L (ES) | 2023-09-27 | — | — | EP | disclosed |
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |