Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23921539 | 0.88 | GPR139 (0.56) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21526187 | 0.88 | GPR139 (0.56) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21555036 | 0.88 | GPR139 (0.56) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21554794 | 0.88 | GPR139 (0.56) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21526219 | 0.87 | GPR139 (0.58) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21554807 | 0.87 | CAPN1 (0.68) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21526220 | 0.87 | GPR139 (0.58) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21526228 | 0.87 | CAPN1 (0.68) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21526229 | 0.87 | CAPN1 (0.68) | GPR139CAPN1MEN1ALDH1A1MAPK1 | |
| SCHEMBL21554817 | 0.87 | GPR139 (0.58) | GPR139CAPN1MEN1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564211-A1 | DIPEPTIDYL KETOAMIDE META-METHOXYPHENYL DERIVATIVES AND USES THEREOF | LANDSTEINER GENMED, S.L. (ES) | 2019-11-06 | — | — | EP | disclosed |