Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.58 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16218784 | 0.92 | TYR (0.60) | TYRCYP19A1HSP90AB1HDAC1NOTUM | |
| SCHEMBL16219151 | 0.84 | TYR (0.60) | TYRCYP19A1HSP90AB1HDAC1HRH4 | |
| SCHEMBL16216237 | 0.84 | CYP19A1 (0.74) | TYRCYP19A1HSP90AB1NOTUM | |
| SCHEMBL30657567 | 0.82 | CYP19A1 (0.72) | CYP19A1HSP90AB1HDAC1HRH4 | |
| SCHEMBL16401421 | 0.77 | TYR (0.59) | TYRCYP19A1NOTUM | |
| SCHEMBL16206208 | 0.77 | CYP19A1 (0.82) | CYP19A1HSP90AB1HDAC1HRH4 | |
| SCHEMBL2194279 | 0.77 | CYP19A1 (0.77) | CYP19A1HSP90AB1HDAC1HRH4 | |
| SCHEMBL16831504 | 0.72 | CYP19A1 (0.69) | CYP19A1HSP90AB1HDAC1HRH4NOTUM | |
| SCHEMBL16219152 | 0.71 | TYR (0.52) | TYRCYP19A1NOTUM | |
| SCHEMBL15795458 | 0.71 | CYP19A1 (0.71) | CYP19A1HSP90AB1HDAC1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3567029-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | Lantheus Medical Imaging, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |