Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16401451 | 0.83 | CYP19A1 (0.61) | CYP19A1NPC1RAB9A | |
| SCHEMBL16401955 | 0.82 | NOTUM (0.65) | KDRROCK2GSK3BAURKBNOTUM | |
| SCHEMBL16401868 | 0.81 | CD74 (0.48) | TYRCYP19A1KCNMA1NPC1RAB9A | |
| SCHEMBL16401596 | 0.81 | SIGMAR1 (0.51) | ROCK2GSK3BAURKBSIGMAR1CYP11B1 | |
| SCHEMBL16219152 | 0.81 | TYR (0.52) | TYRKDRJAK2ROCK2GSK3B | |
| SCHEMBL16218784 | 0.80 | TYR (0.60) | TYRKDRJAK2ROCK2GSK3B | |
| SCHEMBL16219151 | 0.80 | TYR (0.60) | TYRKDRJAK2ROCK2GSK3B | |
| SCHEMBL16216237 | 0.80 | CYP19A1 (0.74) | TYRKDRJAK2ROCK2GSK3B | |
| SCHEMBL16401703 | 0.78 | GPR55 (0.55) | KDRTEK | |
| SCHEMBL21557005 | 0.77 | TYR (0.58) | TYRNOTUMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015007613-A1 | O-ALKYL TRIAZOLYL CARBAMATES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE (FAAH) | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2015-01-22 | — | — | WO | disclosed |