Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672301 | 0.86 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9262044 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9262039 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9674507 | 0.82 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9673058 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL10567203 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9673165 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL10563002 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL30995709 | 0.74 | ALDH1A1 (0.57) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA | |
| SCHEMBL9673356 | 0.73 | SMN1; SMN2 (0.42) | SMN1; SMN2CYP1A2CYP2C19CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419096-B1 | STABILIZATION OF RADIOPHARMACEUTICAL COMPOSITIONS USING ASCORBIC ACID | LANTHEUS MEDICAL IMAGING INC (US) | 2019-11-13 | — | — | EP | disclosed |