Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CNR1 | P21554 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11649834 | 1.00 | LMNA (0.55) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL24331075 | 0.83 | LMNA (0.67) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL21557074 | 0.81 | LMNA (0.43) | LMNACNR1ADRA1ATDP1KDM4E | |
| SCHEMBL11645800 | 0.79 | LMNA (0.50) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL24433260 | 0.74 | LMNA (0.59) | LMNABLMPTPN1MEN1CYP3A4 | |
| SCHEMBL13519647 | 0.74 | LMNA (0.50) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL2961583 | 0.73 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL2636850 | 0.73 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL3399 | 0.73 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E | |
| Ethambutol SCHEMBL15479016 | 0.73 | LMNA (1.00) | LMNACNR1ADRA1ATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166957-B1 | SULFATED-GLYCOLIPIDS AS ADJUVANTS FOR VACCINES | NAT RES COUNCIL CANADA (CA) | 2019-11-13 | — | — | EP | disclosed |