Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557582 | 0.85 | AXL (0.46) | CCR5ABL1BCRCREBBP | |
| SCHEMBL1237447 | 0.73 | TLR8 (0.48) | DHODHKDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL29427899 | 0.71 | MAOA (0.49) | KDM4E | |
| SCHEMBL30641504 | 0.71 | PDK2 (0.39) | DHODHCCR5KDM4EABL1PDK2 | |
| SCHEMBL28676877 | 0.71 | PIK3CD (0.43) | CCR5KDM4EPDK2 | |
| SCHEMBL5713849 | 0.71 | PDK2 (0.42) | CCR5KDM4EPDK2CREBBP | |
| SCHEMBL21599109 | 0.69 | DHODH (0.60) | DHODHCCR5KDM4EKDM6BKDM4A | |
| SCHEMBL28830424 | 0.69 | KDM4E (0.64) | DHODHCCR5KDM4EKDM6BKDM4A | |
| SCHEMBL207017 | 0.69 | KDM4E (0.69) | DHODHKDM4EKDM6BKDM4AKDM5C | |
| SCHEMBL28404844 | 0.69 | KDM4E (0.64) | DHODHCCR5KDM4EKDM6BKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3566749-A1 | THIAZOLE DERIVATIVE AND APPLICATIONS THEREOF | Medshine Discovery Inc. (CN) | 2019-11-13 | — | — | EP | disclosed |