Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17865208 | 0.85 | BACE1 (0.41) | BACE1BACE2 | |
| SCHEMBL10194102 | 0.74 | SMN1; SMN2 (0.42) | BACE1 | |
| SCHEMBL15279730 | 0.74 | BACE1 (0.51) | BACE1BACE2 | |
| SCHEMBL10194904 | 0.73 | SMN1; SMN2 (0.42) | BACE1BACE2 | |
| SCHEMBL10193857 | 0.73 | BACE1 (0.51) | BACE1BACE2 | |
| SCHEMBL10193152 | 0.72 | BACE1 (0.50) | BACE1BACE2 | |
| SCHEMBL16006914 | 0.72 | BACE1 (0.44) | BACE1BACE2 | |
| SCHEMBL10193244 | 0.70 | BACE1 (0.53) | BACE1BACE2 | |
| SCHEMBL10193828 | 0.70 | SMN1; SMN2 (0.59) | BACE1BACE2 | |
| SCHEMBL18517808 | 0.70 | NPC1 (0.68) | BACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233834-B1 | 2,3,4,5-TETRAHYDROPYRIDIN-6-AMINE AND 3,4-DIHYDRO-2H-PYRROL-5-AMINE DERIVATIVES USEFUL AS INHIBITORS OF BETA-SECRETASE | JANSSEN PHARMACEUTICA NV (BE) | 2019-11-13 | — | — | EP | disclosed |