Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | BRD2 | P25440 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 2/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908380 | 0.78 | TSHR (0.41) | TSHRKMT2AKDM4EMAPK1CYP19A1 | |
| SCHEMBL21962885 | 0.78 | TSHR (0.41) | TSHRKMT2AKDM4EMAPK1CYP19A1 | |
| SCHEMBL12381788 | 0.78 | SMN1; SMN2 (0.36) | TLR4PIK3CD | |
| SCHEMBL8222968 | 0.78 | DPP4 (0.33) | TLR4PIK3CDTSHRCYP3A4DPP4 | |
| SCHEMBL25762082 | 0.78 | ACE (0.32) | TLR4PIK3CD | |
| SCHEMBL12856142 | 0.73 | PIK3CD (0.43) | TLR4PIK3CD | |
| SCHEMBL9251987 | 0.71 | MAPK1 (0.37) | TLR4PIK3CDBRD4BRD2MAPK1 | |
| SCHEMBL18821187 | 0.71 | MAPK1 (0.37) | TLR4PIK3CDBRD4BRD2MAPK1 | |
| SCHEMBL18883353 | 0.71 | MAPK1 (0.37) | TLR4PIK3CDBRD4BRD2MAPK1 | |
| SCHEMBL8556280 | 0.71 | PIK3CD (0.35) | PIK3CDBRD4BRD2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235880-A1 | CD38 MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| EP-3566750-A2 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | ImmunoGen, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |