Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557930 | 0.73 | TLR4 (0.33) | PIK3CDTLR4 | |
| SCHEMBL18821187 | 0.70 | MAPK1 (0.37) | PIK3CDTLR4 | |
| SCHEMBL11308573 | 0.70 | RAB9A (0.47) | PIK3CDNPC1MAPTRAB9ANFE2L2 | |
| SCHEMBL9251987 | 0.70 | MAPK1 (0.37) | PIK3CDTLR4 | |
| SCHEMBL11308580 | 0.70 | RAB9A (0.47) | PIK3CDNPC1MAPTRAB9ANFE2L2 | |
| SCHEMBL18883353 | 0.70 | MAPK1 (0.37) | PIK3CDTLR4 | |
| SCHEMBL9908380 | 0.68 | TSHR (0.41) | MAPT | |
| SCHEMBL21962885 | 0.68 | TSHR (0.41) | MAPT | |
| SCHEMBL9463542 | 0.68 | KMT2A (0.38) | PIK3CDMAPT | |
| SCHEMBL18651543 | 0.67 | BRD4 (0.38) | PIK3CDTLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664092-B1 | MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS NS3 SERINE PROTEASE | SCHERING CORP (US) | 2011-02-02 | — | — | EP | disclosed |