SCHEMBL2156201

SCHEMBL2156201

Cc1c(C)c(N2C(=O)c3ccc(C(C)(C)C)cc3C2=O)c(C)c(C)c1N1C(=O)c2ccc(C(C)(C)C)cc2C1=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA9 Q16790 6/20 0.56
CA1 P00915 4/20 0.56
CA12 O43570 3/20 0.56
CA2 P00918 4/20 0.55
NPC1 O15118 2/20 0.47
ALDH1A1 P00352 2/20 0.47
RAB9A P51151 2/20 0.47
PLA2G1B P04054 1/20 0.47
NFKB1 P19838 1/20 0.47
CASP3 P42574 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SENP8 Q96LD8 1/20 0.47
SENP7 Q9BQF6 1/20 0.47
SENP6 Q9GZR1 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ATG4B Q9Y4P1 1/20 0.47
ANPEP P15144 3/20 0.44
DPP4 P27487 3/20 0.44
CA4 P22748 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12204692 0.91 CA9 (0.49) CA9CA1CA12CA2NPC1
SCHEMBL6925061 0.79 ANPEP (0.66) CA9CA1CA12CA2NPC1
SCHEMBL2759723 0.78 CA9 (0.38) CA9CA1CA12CA2ALDH1A1
SCHEMBL15043753 0.78 NR1H3 (0.58) CA9CA1CA12CA2NPC1
SCHEMBL12204809 0.78 CA9 (0.38) CA9CA1CA12CA2NPC1
SCHEMBL22022263 0.77 CA9 (0.53) CA9CA1CA12CA2NPC1
SCHEMBL19702942 0.77 CA9 (0.53) CA9CA1CA12CA2NPC1
SCHEMBL19323393 0.77 CA9 (0.37) CA9CA1CA12CA2NPC1
SCHEMBL13008158 0.76 ANPEP (0.43) CA9CA1CA12CA2NPC1
SCHEMBL16019265 0.76 APP (0.38) CA9CA1CA12CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8399109-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-03-19 US disclosed
US-8399109-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-03-19 US disclosed
US-8399109-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2013-03-19 US disclosed
US-20130025684-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2013-01-31 US disclosed
US-20130025684-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2013-01-31 US disclosed
US-20130025684-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2013-01-31 US disclosed
EP-2378586-B1 Organic electronic devices using phthalimide compounds UNIV SOUTHERN CALIFORNIA (US) 2012-11-21 EP disclosed
US-8293385-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-10-23 US disclosed
US-8293385-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-10-23 US disclosed
US-8293385-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2012-10-23 US disclosed
US-20100300538-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2010-12-02 US disclosed
US-20100300538-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2010-12-02 US disclosed
US-20100300538-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS ENERGY, UNITED STATES DEPARTMENT OF 2010-12-02 US disclosed
US-7790298-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2010-09-07 US disclosed
US-7790298-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2010-09-07 US disclosed
US-7790298-B2 Organic electronic devices using phthalimide compounds THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2010-09-07 US disclosed
US-20090107551-A1 Organic electronic devices using phthalimide compounds ENERGY, U.S. DEPARTMENT OF 2009-04-30 US disclosed
US-20090107551-A1 Organic electronic devices using phthalimide compounds ENERGY, U.S. DEPARTMENT OF 2009-04-30 US disclosed
US-20090107551-A1 Organic electronic devices using phthalimide compounds ENERGY, U.S. DEPARTMENT OF 2009-04-30 US disclosed
WO-2007120788-A1 ORGANIC ELECTRONIC DEVICES USING PHTHALIMIDE COMPOUNDS THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2007-10-25 WO disclosed