SCHEMBL16019265

SCHEMBL16019265

Cc1c(C)c(C)c(N2C(=O)c3ccc(C(c4ccc5c(c4)C(=O)N(C)C5=O)(C(F)(F)F)C(F)(F)F)cc3C2=O)c(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.38
ALDH1A1 P00352 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HPGD P15428 1/20 0.38
MAPK1 P28482 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
ANPEP P15144 2/20 0.37
DPP4 P27487 2/20 0.37
ALOX15 P16050 1/20 0.36
CA9 Q16790 3/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13008162 0.92 ANPEP (0.39) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL20886666 0.92 ANPEP (0.38) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL15493904 0.90 ANPEP (0.36) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL26801078 0.89 CA2 (0.41) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL2759723 0.88 CA9 (0.38) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL4549126 0.87 ALDH1A1 (0.47) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL13008158 0.86 ANPEP (0.43) ALDH1A1MEN1KMT2AHSD17B10MAPK1
SCHEMBL822115 0.85 ANPEP (0.33) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL12260131 0.84 ALDH1A1 (0.51) APPALDH1A1MEN1MAPTKMT2A
SCHEMBL26800971 0.84 NR1H3 (0.37) APPALDH1A1MEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240024828-A1 HALOGEN-SUBSTITUTED 9,9-BIS(4-AMINOPHENYL)FLUORENE BASED POLYIMIDE MEMBRANES FOR GAS SEPARATION APPLICATIONS SAUDI ARABIAN OIL COMPANY (SA) 2024-01-25 US disclosed
US-20240024828-A1 HALOGEN-SUBSTITUTED 9,9-BIS(4-AMINOPHENYL)FLUORENE BASED POLYIMIDE MEMBRANES FOR GAS SEPARATION APPLICATIONS SAUDI ARABIAN OIL COMPANY (SA) 2024-01-25 US disclosed
US-20230182070-A1 STACKED MEMBRANES AND THEIR USE IN GAS SEPARATION SAUDI ARABIAN OIL COMPANY (SA) 2023-06-15 US disclosed
WO-2023082450-A1 PREPARATION METHOD FOR THERMAL CROSS-LINKED POLYMER SEPARATION MEMBRANE AND APPLICATION THEREOF 苏州大学 2023-05-19 WO disclosed
US-20170252720-A1 MODIFICATION OF ZEOLITIC IMIDAZOLATE FRAMEWORKS AND AZIDE CROSS-LINKED MIXED-MATRIX MEMBRANES MADE THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-09-07 US disclosed
US-9522364-B2 Treated mixed matrix polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-20 US disclosed
US-9492785-B2 UV and thermally treated polymeric membranes SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-11-15 US disclosed
US-20160263532-A1 ULTRAVIOLET AND PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263533-A1 TREATED MIXED MATRIX POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160263531-A1 PLASMA-TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-15 US disclosed
US-20160250585-A1 UV AND THERMALLY TREATED POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-09-01 US disclosed
US-20150101986-A1 MIXED MATRIX POLYMERIC MEMBRANES SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-04-16 US disclosed
US-20140255636-A1 Polymeric Membranes SAUDI BASIC INDUSTRIES CORPORATION (SA) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150101986-A1 MIXED MATRIX POLYMERIC MEMBRANES VIM, EPCAM, PICALM APP 4727/4885ALDH1A1 4645/4885MEN1 2198/4885
US-20170252720-A1 MODIFICATION OF ZEOLITIC IMIDAZOLATE FRAMEWORKS AND AZIDE CROSS-LINKED MIXED-MATRIX MEMBRANES MADE THEREFROM ITGAM, HNMT, WASF2 APP 4755/4885ALDH1A1 3831/4885MEN1 1198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.