Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 13/20 | 0.48 |
| ▸ | SYK | P43405 | 2/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21550918 | 0.91 | FURIN (0.48) | FURINSYKCKS1BSKP1SKP2 | |
| SCHEMBL29890885 | 0.89 | FURIN (0.47) | FURINSYKCKS1BSKP1SKP2 | |
| SCHEMBL21550916 | 0.89 | FURIN (0.48) | FURINSYKCKS1BSKP1SKP2 | |
| SCHEMBL28544841 | 0.89 | CKS1B (0.47) | FURINSYKCKS1BSKP1SKP2 | |
| SCHEMBL21564580 | 0.88 | CKS1B (0.47) | FURINSYKCKS1BSKP1SKP2 | |
| SCHEMBL29928359 | 0.84 | FURIN (0.49) | FURIN | |
| SCHEMBL21551606 | 0.84 | FURIN (0.49) | FURIN | |
| SCHEMBL30931829 | 0.82 | FURIN (0.53) | FURINCKS1BSKP1SKP2RET | |
| SCHEMBL21551754 | 0.82 | FURIN (0.53) | FURINCKS1BSKP1SKP2RET | |
| SCHEMBL29890982 | 0.82 | FURIN (0.53) | FURINCKS1BSKP1SKP2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |