Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 12/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | PGK1 | P00558 | 1/20 | 0.46 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | RET | P07949 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890947 | 0.92 | FURIN (0.55) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL30931806 | 0.92 | FURIN (0.55) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL21551238 | 0.92 | FURIN (0.55) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL29890812 | 0.91 | GPR119 (0.53) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL21551434 | 0.91 | GPR119 (0.53) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL21551754 | 0.90 | FURIN (0.53) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL30931829 | 0.90 | FURIN (0.53) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL29890982 | 0.90 | FURIN (0.53) | FURINGPR119PGK1ADKCKS1B | |
| SCHEMBL21564518 | 0.88 | FURIN (0.55) | FURIN | |
| SCHEMBL27044993 | 0.88 | GPR119 (0.54) | GPR119PGK1ADKCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3790871-B1 | FURIN INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019215341-A1 | FURIN INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-11-14 | — | — | WO | disclosed |
| US-9388132-B2 | Isobaric tandem mass tags for quantitative proteomics and peptidomics | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-07-12 | — | — | US | disclosed |