SCHEMBL21564444

SCHEMBL21564444

CN1CCCN(c2ncc(Oc3cc(CN4CCC5CC5CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30792572 1.00 FURIN (0.79) FURIN
SCHEMBL30792571 0.97 FURIN (0.78) FURIN
SCHEMBL27032408 0.90 FURIN (0.78) FURIN
SCHEMBL21551472 0.88 FURIN (1.00) FURIN
SCHEMBL29928460 0.88 FURIN (0.81) FURIN
SCHEMBL21550705 0.88 FURIN (0.81) FURIN
SCHEMBL29928407 0.88 FURIN (1.00) FURIN
SCHEMBL21551059 0.88 FURIN (0.82) FURIN
SCHEMBL21551216 0.88 FURIN (0.87) FURIN
SCHEMBL21551057 0.88 FURIN (0.82) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP disclosed
WO-2019215341-A1 FURIN INHIBITORS GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2019-11-14 — — WO disclosed
Send feedback