SCHEMBL30792571

SCHEMBL30792571

CN1CCN(c2ncc(Oc3cc(CN4CC[C@@H]5C[C@@H]5CC4)cc(-c4cc(Cl)cc(Cl)c4)n3)cn2)CC1

nearest known ligand 0.78

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FURIN P09958 20/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30792572 0.97 FURIN (0.79) FURIN
SCHEMBL21564444 0.97 FURIN (0.79) FURIN
SCHEMBL27032408 0.93 FURIN (0.78) FURIN
SCHEMBL27031825 0.90 FURIN (0.75) FURIN
SCHEMBL26077940 0.90 FURIN (0.75) FURIN
SCHEMBL21564707 0.89 FURIN (0.72) FURIN
SCHEMBL30792570 0.89 FURIN (0.65) FURIN
SCHEMBL21550717 0.88 FURIN (0.81) FURIN
SCHEMBL21564687 0.88 FURIN (0.78) FURIN
SCHEMBL29928208 0.88 FURIN (0.81) FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790871-B1 FURIN INHIBITORS GLAXOSMITHKLINE IP DEV LTD (GB) 2024-01-24 — — EP claimed
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