Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21564488 | 0.92 | SYK (0.33) | SYKMEN1KMT2A | |
| SCHEMBL21564817 | 0.84 | ALDH1A1 (0.35) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21564502 | 0.83 | — | — | |
| SCHEMBL21564498 | 0.83 | SYK (0.33) | SYK | |
| SCHEMBL21564837 | 0.82 | HRH4 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21564512 | 0.80 | ESR1 (0.30) | — | |
| SCHEMBL21564626 | 0.80 | CHEK1 (0.36) | SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL21564650 | 0.80 | ESRRB (0.36) | MEN1KMT2AALDH1A1 | |
| SCHEMBL23258181 | 0.79 | JAK2 (0.39) | SYKMEN1KMT2AALDH1A1 | |
| SCHEMBL23258205 | 0.78 | SYK (0.39) | SYKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217972-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2019-11-14 | — | — | WO | disclosed |