Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | FLT3 | P36888 | 3/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21553124 | 0.89 | HDAC6 (0.44) | CYP11B1CYP11B2SOS1FSCN1HDAC6 | |
| SCHEMBL21564557 | 0.88 | CYP11B1 (0.44) | CYP11B1CYP11B2ALDH1A1MAPTBRD4 | |
| SCHEMBL21553162 | 0.85 | KDM1A (0.42) | CYP11B1CYP11B2SRCFLT3FYN | |
| SCHEMBL21564667 | 0.84 | ALDH1A1 (0.33) | NPSR1ALDH1A1MAPT | |
| SCHEMBL21564673 | 0.83 | CYP11B1 (0.42) | CYP11B1CYP11B2SRCFLT3FYN | |
| SCHEMBL21564851 | 0.82 | CYP11B1 (0.41) | CYP11B1CYP11B2SRCFLT3FYN | |
| SCHEMBL21564668 | 0.82 | SRC (0.44) | SRCFLT3FYNSOS1HDAC6 | |
| SCHEMBL21553021 | 0.80 | GAA (0.42) | CYP11B1CYP11B2HDAC6BRD4 | |
| SCHEMBL21564672 | 0.79 | CYP11B1 (0.39) | CYP11B1CYP11B2HDAC6NPSR1BRD4 | |
| SCHEMBL21564585 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019217972-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2019-11-14 | — | — | WO | disclosed |